Jayme E. Locke, MD, MPH, FACS, FAST
Vice President, Medical Development, Xenotransplantation | United Therapeutics
Adjunct Professor of Surgery | NYU Langone Health
Member, American Society of Clinical Investigation
Dr. Locke is a nationally and internationally respected abdominal transplant surgeon who has dedicated her career to studying chronic disease prevention and reversal and access to and outcomes after transplantation through policy change and translating innovative therapies from bench to bedside, including the development of the Parsons Model which has catapulted xenotransplantation into the realm of reality. She is also an accomplished leader and mentor known for building highly effective teams defined by a collaborative spirit, discovery-driven learning, and integrative decisions. Her prolific career has directly impacted the field of transplantation, improving the lives of countless patients.
Research Impact.
• Authored over 215 peer-reviewed articles including high impact publications in the New England Journal of Medicine, Journal of the American Medical Association (JAMA), Journal of Clinical Investigation, and Nature Communications.
• Served as Primary or Co-Investigator of multiple NIH awards totaling over $25M in funding
• Given more than 200 national and international lectures, including the Joseph Murray Visiting Professor, Brigham and Women’s Hospital, Harvard University.
• Testified to the U.S. Senate on the need to modernize the national transplant system: Senate Hearing on Organ Donation and Transplants | C-SPAN.org
• Leveraged innovation to help solve major healthcare challenges, including the organ shortage: https://nyulangone.org/news/gene-edited-pig-kidney-gives-living-donor-new-lease-life https://www.wbaltv.com/article/alabama-woman-pig-kidney-transplant/63213301
Leadership Experience.
• Director, Division of Transplantation | Department of Health and Human Services | Health Resources and
Services Administration | Health Systems Bureau
• Arnold G. Diethelm MD Endowed Chair in Transplantation Surgery | University of Alabama at Birmingham
• Director, Comprehensive Transplant Institute | UAB Medicine | UAB Hospital
• Associate Chief Medical Officer | UAB Medicine | UAB Hospital
• Councilor-at-Large, American Society of Transplant Surgeons
• Councilor-at-Large, Society of University Surgeons
Education and Training.
• Bachelor of Science (cum laude): Duke University
• Master of Public Health: Johns Hopkins Bloomberg School of Public Health
• MD: East Carolina University Brody School of Medicine, Brody Scholar (full scholarship)
• Residency: Johns Hopkins Hospital
• Abdominal Transplant Fellowship: Johns Hopkins Hospital
Awards and Honors.
• Member, American Society of Clinical Investigation
• National Kidney Foundation 2025 Excellence in Transplantation Award
• Association for Clinical & Translational Science Distinguished Investigator Award: Translation into Public Benefit and Policy
• American Society of Transplantation Clinical Science Faculty Award
• AL.com’s Women Who Shape the State
• Birmingham Business Journal’s Top 40 under 40 and Top 10 for the Decade
• James IV Traveling Fellow