411.9 Long-term outcomes of percutaneous stent angioplasty for vein stenosis after pediatric liver transplantation

Min Kyoung Kim, Korea

Fellow
Department of Hepatobiliary-Pancreas Surgery
Seoul National University Hospital

Abstract

Long-term outcomes of percutaneous stent angioplasty for vein stenosis after pediatric liver transplantation

Jiyoung Kim1, Suk Kyun Hong1, Gayoung Kim1, Min Kyoung Kim1, Sang Hyuk Park1, Jae Yoon Kim1, Su young Hong1, YoungRok Choi1, Nam-Joon Yi1, Kwang-Woong Lee1.

1Department of Surgery, Seoul National University College of Medicine, Seoul, Korea

Background: Hepatic and portal vein stenosis are rare but critical complications after pediatric liver transplantation. While stent angioplasty is a viable treatment option, its use in children requires careful consideration due to ongoing vascular growth. This study aims to evaluate the long-term outcomes of pediatric liver transplant recipients who underwent stent placement for venous stenosis.
Methods: Among 266 pediatric liver transplant recipients (1999–2023), 19 underwent stent insertion for venous complications. This study retrospectively analyzed long-term outcomes of 14 patients with follow-up exceeding five years after stenting [median 7.5 (5–24) years].
Results: Seven patients had portal vein stenting, and seven had hepatic vein stenting, with a median interval of 54 days post-transplant. 12 patients (85.7%) showed prolonged ascites, and 8 patients (57.1%) had elevated liver enzymes on laboratory tests leading to stenting after transplantation. Although statistically insignificant, portal vein stenting cases demonstrated a higher proportion (71.4%) of primary stenting procedures compared to hepatic vein stenting (14.3%) cases, likely due to notable size discrepancies between graft and recipient portal veins. The primary patency rates were 85.7% at one year and 78.6% at five years. Reintervention free rate remained stable at 85.7% from one to five years after stenting. All seven patients with follow-up beyond 10 years maintained 100% patency. No procedure-related complications or mortality occurred, though one patient required retransplantation due to graft failure.
Conclusion: Percutaneous stent angioplasty is an effective and safe intervention for pediatric liver transplant recipients experiencing vein stenosis, demonstrating sustained patency and minimal complications in long-term follow-up.

References:

[1] Pediatric Transplantation
[2] Portal Vein Stenosis
[3] Hepatic Vein Stenosis
[4] Stent Insertion
[5] Percutaneous Transluminal Angioplasty

Email: info@ipta2025.org
514-874-1717